Pediatric Oncology Research Project

What makes a child
happy during
cancer treatment?

An evidence-based investigation into the practices that improve daily well-being for pediatric cancer patients, and a proposal for an institution that addresses each of the outlined practices.

"I was always happy and excited to be at the place where I was getting treatment. But there were a lot of people there who were not having nearly as good a time as I was. That last part has stuck with me throughout my life."

Sander  ·  Burkitt's non-Hodgkin Lymphoma survivor, age 4
Sophomore, Grace Church School, New York City

7 Evidence-Based Practices
10 Expert Respondents
4.7 Avg Belief Score (out of 5)
2 Formal Proposals
100% Agreement All Practices Help

What the research determined

Survey respondents — including doctors, nurses, non-profit program directors, and volunteers from MSK and Project Sunshine — rated each of these practices on a scale of 1–5 for their contribution to patient happiness. Every single practice scored 4 or above.

01
Genuine Connections
Avg Belief: 4.9 / 5

Patients are happier when they form genuine bonds with the people around them during treatment. Social support is one of the strongest predictors of emotional resilience in pediatric oncology — research shows children with cancer who experience trusting relationships with staff demonstrate better overall psychological adjustment.[1] During my time in treatment I was lucky enough to have people who really cared about me, and who I really cared about. One of those people was my primary nurse. I was the ring bearer at her wedding several years after I was cured, and this was naturally the first category I thought of when determining where this project would go. If my research confirms anything, it is that connections with caregivers are necessary.

02
Play
Avg Belief: 5.0 / 5

Playful interventions reduce anxiety during medical procedures, improve treatment compliance, and give children a sense of normalcy. Certified Child Life Specialists use play-based approaches that have been shown to improve well-being across chronic illness and long-term hospitalizations.[2] The Play Room at MSK is a great example of this. I have a lot of memories from there.

03
Art Therapy
Avg Belief: 4.6 / 5

A 2025 systematic review and meta-analysis of 452 patients across five countries found statistically significant reductions in anxiety and depression among children who received art therapy.[3] Despite this, most hospital art programs rely on philanthropic funding.

04
Modern, Light Spaces
Avg Belief: 4.3 / 5

Natural light reduces depression, regulates circadian rhythms, and is associated with shorter hospital stays. A comprehensive review by the Center for Health Design found that patients in sun-facing rooms had meaningfully shorter lengths of stay.[4] On the first day of my treatment, when they were doing tests, there was a room with a retractable light and I just remember looking up and thinking "cool." I was interested in whether these spaces could actually be stress-reducing.

05
Healthy, Tasty Food
Avg Belief: 4.2 / 5

Nutritional status directly impacts quality of life, treatment tolerance, and long-term outcomes. Research confirms that malnutrition is prevalent in pediatric cancer patients and adversely affects health-related quality of life.[5] The point is food is such a big part of living happily. Everyone likes food a specific way, and I believe hospital food should maybe be prioritized more.

06
Family Support
Avg Belief: 5.0 / 5

When families feel supported, patients cope better and are happier. Research from Nemours Children's Health found that when families feel their emotional and social needs are met, their children tend to do better in treatment.[6] During my time in recovery, my parents — but more specifically, my mother — really took on a lot of responsibility for my care, and I think that if more support was offered it would have been beneficial to both of our mental recoveries.

07
Animal-Assisted Therapy
Avg Belief: 4.56 / 5

A multisite randomized controlled trial found that parents of children receiving therapy dog visits showed significantly decreased parenting stress. The human-animal bond stimulates oxytocin release and reduces cortisol.[7] However, some studies note limitations in sample size and the need for more research.[8] As someone who really loves animals, when I was developing this question it came from a place of curiosity — because I never had animal therapy.

The scores speak for themselves

All seven practices were rated between 4.0 and 5.0 by respondents — signaling a rare level of expert consensus. The more important finding: institutions are not fully delivering on what the evidence demands.

Connections4.9
Play5.0
Art Therapy4.6
Modern Spaces4.3
Healthy Food4.2
Family Support5.0
Animal Therapy4.56
Key Insight #1
Unanimous expert agreement across all seven practices

Every respondent — from a doctor at Memorial Sloan Kettering to program directors at Project Sunshine — gave every practice a rating of 3 or above. Most rated them 4 or 5. There is a rare and powerful consensus here.

Key Insight #2
There are implementation gaps

When asked how well their institution performs these practices, scores were consistently lower than belief scores — particularly for Animal Therapy and Food. This gap is the central argument for action: the evidence is there, but it isn't being fully put into practice.

Key Insight #3
Non-profits are filling the gap, but not enough

Respondents from non-profits (Project Sunshine) and hospitals (MSK) showed different patterns. Non-profit professionals rated their institutional performance higher on art and play. This points to a clear division of labor and a clear opportunity for more non-profit involvement.

What this means
There are two proposals, and they both seek to better help the patients

These findings led to two tailored proposals: one for hospitals seeking to strengthen their internal practices, and one for non-profits looking for evidence-based programs to fund or implement in partnership with hospitals.

The two proposals

Each proposal is for a specific audience but both focus on my original research, peer-reviewed studies, and the belief that every child deserves to be happy during treatment.

🏥 For Hospitals
Pediatric Oncology Patient Wellness Proposal

A case for implementing and strengthening all seven practices within a hospital's pediatric oncology department including specific recommendations for each.

  • Research synthesis for all 7 practices with citations
  • Specific implementation recommendations per practice
  • Survey data analysis and expert respondent findings
  • Framed for hospital administration and department heads
Download Hospital Proposal
🤝 For Non-Profits
Partnership in Pediatric Oncology Patient Wellness

A partnership proposal identifying where non-profit organizations can fill the gap between what hospitals know works and what they can actually afford to offer — with three partnership models to choose from.

  • Practice-by-practice non-profit opportunity analysis
  • Three partnership models: adoption, research, or advocacy
  • Centered on the implementation gap from survey data
  • Framed for non-profit leadership and program officers
Download Non-Profit Proposal

It started as a personal interest of mine

I had Burkitt's non-Hodgkin Lymphoma when I was four, and during treatment, I was always happy and excited to be at the place I was getting treatment. However, there were a lot of people there who were not having nearly as good a time as I was. That last part has stuck with me throughout my life. For this project, I aimed to learn more about how hospitals enhance the daily lives of pediatric cancer patients and how outside organizations contribute to this effort, and I want to see if there is room for improvement in the methods that are employed to help kids feel happier during treatment.

The definition of happiness I used throughout: a genuine interest in offerings, visible contentment, and a subjective sense of well-being. Because happiness during cancer treatment is specific — and it matters more than people may realize.

S
Sander
Student Researcher · Grace Church School
Pediatric Cancer Survivor New York City Class of 2028 Pediatric Oncology Survey Research Nonprofit Advocacy

Sources

All seven practices identified in this project are supported by peer-reviewed academic literature. The following sources were consulted in the development of this research and the two formal proposals.

Connections & Psychosocial Support
[1]
Fostering the Psychological Wellbeing of Children Diagnosed with Cancer: Multidisciplinary Insights in Pediatric Oncology
PMC / Frontiers in Psychology, 2025  ·  View Source
Confirms that social support and trusting relationships with staff are among the strongest predictors of psychological adjustment in pediatric oncology patients.
[1b]
Supportive Care in Pediatric Oncology: Opportunities and Future Directions
PMC, 2023  ·  View Source
Highlights structured communication and trust-building as essential to improving quality of life throughout the cancer trajectory.
Play
[2]
Playful Strategies to Foster the Well-Being of Pediatric Cancer Patients in the Brazilian Unified Health System: A Design Thinking Approach
BMC Health Services Research, 2021  ·  View Source
Documents that play-based strategies stimulate treatment compliance and provide critical psychosocial support for pediatric cancer patients.
[2b]
Playful Interventions to Promote the Subjective Wellbeing of Pediatric Cancer Inpatients During Laboratory and Imaging Exams
ScienceDirect, 2022  ·  View Source
Using the PERMA-V model, finds that playful interventions during procedures significantly reduce fear and anxiety in hospitalized children.
Art Therapy
[3]
Effects of Art Therapy on Psychological Outcomes Among Children and Adolescents with Cancer: A Systematic Review and Meta-Analysis
BMC Complementary Medicine and Therapies, 2025  ·  View Source
Meta-analysis of 452 participants across five countries showing statistically significant improvement in anxiety and depression. Narrative findings also suggested improvements in stress and anger.
[3b]
Creative Art Therapy Lessens Anxiety in Pediatric Patients with Cancer
Oncology Nursing News / Cancer Nursing, 2024  ·  View Source
Study of 83 patients ages 3–17 found longitudinal improvement in anxiety after four or more art therapy sessions. Notes that nurses can facilitate art interventions without specialized training.
[3c]
Art Therapy During Childhood Cancer
St. Jude Children's Research Hospital  ·  View Source
Clinical resource confirming that art therapy reduces anxiety, depression, and pain while improving quality of life, communication, and coping skills in pediatric cancer patients.
Modern, Light Spaces
[4]
Impact of Light on Outcomes in Healthcare Settings
The Center for Health Design, 2006  ·  View Source
Comprehensive review linking natural and artificial light to health outcomes including depression, sleep regulation, circadian rhythms, and length of stay in hospital patients.
[4b]
The Influence of Exposure to Nature on Inpatient Hospital Stays: A Scoping Review
PMC, 2024  ·  View Source
Finds that nature exposure — windows, murals, plants — reduces anxiety, lowers heart rate and blood pressure, and improves patient satisfaction during hospitalization.
Nutrition & Food
[5]
Role of Nutrition in Pediatric Patients with Cancer
PMC, 2023  ·  View Source
Confirms that nutritional status directly influences quality of life, treatment tolerance, immune function, and overall survival in pediatric cancer patients. Argues malnutrition should not be accepted as inevitable.
[5b]
Nutritional Status of Pediatric Cancer Patients at Diagnosis and Correlations with Treatment, Clinical Outcome and Long-Term Growth
PMC, 2020  ·  View Source
Documents that malnutrition adversely affects health-related quality of life and that early nutritional intervention can minimize treatment side effects.
Family Support
[6]
Family-Centered Support in Pediatric Cancer
Nemours Children's Health Blog, 2025  ·  View Source
Research letter published in JAMA Pediatrics found that when families feel their emotional and social needs are met, children tend to do better in treatment. Identifies family support as a top priority for providers.
[6b]
Resilience-Promoting Programs in Families of Children with Cancer: A Systematic Review
Journal of Pediatric Hematology/Oncology Nursing, 2022  ·  View Source
Systematic review finding that family resilience programs — providing psychoeducation and emotional coping support — reduce anxiety and depression and improve family adaptation.
Animal-Assisted Therapy
[7]
Measuring the Effects of an Animal-Assisted Intervention for Pediatric Oncology Patients and Their Parents: A Multisite Randomized Controlled Trial
Journal of Pediatric Oncology Nursing, 2018  ·  View Source
Randomized trial of 106 pediatric cancer patients found that parents in the therapy dog group showed significantly decreased parenting stress. Supports the role of animal-assisted therapy in family-centered care.
[8]
A Randomized Controlled Trial of Animal-Assisted Activities for Pediatric Oncology Patients: Psychosocial and Microbial Outcomes
Journal of Pediatric Health Care, 2024  ·  View Source
Contrasting source: NIH-funded RCT that did not detect a statistically significant effect on patient psychological functioning, though noted the study was underpowered after closing early due to COVID-19. Did find reduced parental anxiety and no significant microbial transfer with proper hand sanitization.
[8b]
Animal-Assisted Interventions for Children with Advanced Cancer: Child and Parent Perceptions
Palliative Medicine Reports, 2021  ·  View Source
Qualitative study finding that 95% of participants — children with advanced cancer and their parents — reported positive experiences with animal-assisted interventions. The only complaint: visits were too short.